Despite the best antibiotics and intensive care, sepsis is the primary cause of death from infection. And sepsis cases are increasing, up by between 8% and 13% over the last decade, claiming more lives than bowel and breast cancer combined.

1.3 Million

Sepsis cases a year

in the US alone

30-50%

fatality rate

$23.7 BILLION

in treatment

costs a year

Source: HCUP Statistical Brief #204 (May 2016)

CLINICALLY ACTIONABLE RESULTS IN 3-4 HOURS

Dialog with over 100 practicing clinicians and lab directors has confirmed the potential value and impact of LiDia-SEQ™ in combating sepsis. As a result, our semiconductor sequencing platform will launch initially with a groundbreaking test for bloodstream infections (BSI) and antimicrobial resistance (AMR), which uses whole blood specimens to detect and identify infections that lead to sepsis.

 

By rapidly identifying what infection a patient has, as well as any associated antimicrobial resistance, our test will provide clinicians with actionable information to help them select the best antibiotics to treat the disease.

It usually takes between 2-6 days to diagnose bloodstream infections using a blood culture, depending on whether the microbe is bacterial or fungal, during which time clinicians have only empirical treatment options.

 

DNAe’s BSI/AMR test takes approximately 3-4 hours to complete and with regulatory clearance can deliver actionable results to the clinician at the point-of-need.

Urgent need: Mortality increases 7.6+% for every hour after onset of hypotension. Kumar et al. (2006) Critical Care Med.

Focused and fast

 

This one breakthrough test is enough to identify a broad range of possible bloodstream infectious organisms, as well as a selection of antimicrobial resistance genes.

 

Because microbial pathogens may be present at very low concentrations in the blood of infected patients (1 colony-forming unit per ml), the BSI/AMR test incorporates a sample preparation stage capable of extracting microbial DNA from a vacutainer of blood, which is subsequently amplified and identified.

By accurately diagnosing infections at an earlier stage, we can help to save the lives of patients.

COMPANY DETAILS

 

Email: contact@dnae.com

Switchboard: +44 (0)20 7036 2100

Twitter: @dna_electronics

OFFICE  LOCATIONS

DNAe Group Holdings Ltd

Ugli Campus Block C

56 Wood Lane

London

W12 7SB

United Kingdom

 

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DNA Electronics, Inc.

1891 Rutherford Road

Suite 100

Carlsbad, CA 92008

USA

+1 (760) 444-9410

 

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