Despite the best antibiotics and intensive care, sepsis is the primary cause of death from infection. And sepsis cases are increasing, up by between 8% and 13% over the last decade, claiming more lives than bowel and breast cancer combined.
Despite the best antibiotics and intensive care, sepsis is the primary cause of death from infection. And sepsis cases are increasing, up by between 8% and 13% over the last decade, claiming more lives than bowel and breast cancer combined.
Despite the best antibiotics and intensive care, sepsis is the primary cause of death from infection. And sepsis cases are increasing, up by between 8% and 13% over the last decade, claiming more lives than bowel and breast cancer combined.
Dialog with over 100 practicing clinicians and lab directors has confirmed the potential value and impact of LiDia-SEQ™ in combating sepsis. As a result, our semiconductor sequencing platform will launch initially with a groundbreaking test for bloodstream infections (BSI) and antimicrobial resistance (AMR), which uses whole blood specimens to detect and identify infections that lead to sepsis.
By rapidly identifying what infection a patient has, as well as any associated AMR, our test will provide clinicians with actionable information to help them select the best antibiotics to treat the disease.
It usually takes between 2-6 days to diagnose BSI using a blood culture, depending on whether the microbe is bacterial or fungal, during which time clinicians have only empirical treatment options.
DNAe’s BSI/AMR test takes approximately 3-4 hours to complete and with regulatory clearance can deliver actionable results to the clinician at the point-of-need.
This one breakthrough test is enough to identify a broad range of possible bloodstream infectious organisms, as well as a selection of antimicrobial resistance genes.
Because microbial pathogens may be present at very low concentrations in the blood of infected patients (1 colony-forming unit per ml), the BSI/AMR test incorporates a sample preparation stage capable of extracting microbial DNA from a vacutainer of blood, which is subsequently amplified and identified.