Sepsis

Despite the best antibiotics and intensive care, sepsis is the primary cause of death from infection. And sepsis cases are increasing, up by between 8% and 13% over the last decade, claiming more lives than bowel and breast cancer combined.

1.3 Million

Sepsis cases a year

in the US alone

30-50%

fatality rate

$23.7 BILLION

in treatment

costs a year

Source: HCUP Statistical Brief #204 (May 2016)

It usually takes between 2 and 6 days to diagnose blood infections using a blood culture, depending whether the microbe is bacterial or fungal. While organisms culture in the laboratory, treatment remains empirical.

The LiDia® Bloodstream Infection (BSI) test takes about 3 hours to complete and an actionable result is delivered in time to the effectiveness of treatment.

ACTIONABLE RESULTS

DELIVERED TO THE

CLINICIAN IN 3 HOURS

Urgent need: Mortality increases 7.6+% for every hour after onset of hypotension. Kumar et al. (2006) Critical Care Med.

Focused and fast

Dialog with over 100 practising clinicians and lab directors has confirmed the potential value and impact of LiDia: making it quick and simple to get patients with suspected bloodstream infection treated with the best therapy.

The LiDia bloodstream infection test will analyze a blood sample directly from an uncultured specimen. This is a breakthrough: one test is enough to identify a broad range of possible bloodstream infectious organisms, as well as a selection of antimicrobial resistance genes. Because microbial pathogens in blood infections may be present at very low concentrations (1 colony-forming unit per ml), LiDia for bloodstream infection incorporates a sample preparation stage capable of extracting microbial DNA from a vacutainer of blood, which is subsequently amplified and identified.