![5fca36d580071694554a6181_sepsis](https://www.dnae.com/wp-content/uploads/2024/03/5fca36d580071694554a6181_sepsis.webp)
![5fca36d580071609c24a6167_DNAe_WM_SEPSIS](https://www.dnae.com/wp-content/uploads/2024/03/5fca36d580071609c24a6167_DNAe_WM_SEPSIS.webp)
Despite the best antibiotics and intensive care, sepsis is the primary cause of death from infection. And sepsis cases are increasing, up by between 8% and 13% over the last decade, claiming more lives than bowel and breast cancer combined.
![5fd0f03c276e12253f95f6f0_Sepsis 2 liner-p-500](https://www.dnae.com/wp-content/uploads/2024/03/5fd0f03c276e12253f95f6f0_Sepsis-2-liner-p-500.webp)
![](https://www.dnae.com/wp-content/uploads/2024/03/5fca36d5800716ab8d4a6184_pasted-image-102x103-1.webp)
2 Million
Sepsis cases a year
in the US alone
![](https://www.dnae.com/wp-content/uploads/2024/03/5fca36d580071620e84a6183_pasted-image-104x102-1.webp)
30-50%
fatality rate
![](https://www.dnae.com/wp-content/uploads/2024/03/5fca36d580071610fe4a6182_pasted-image-103x107-1.webp)
$38.2 BILLION
in treatment
costs a year
Source: HCUP Statistical Brief #261 (July 2020)
Dialog with over 100 practicing clinicians and lab directors has confirmed the potential value and impact of LiDia-SEQ™ in combating sepsis. As a result, our semiconductor sequencing platform will launch initially with a groundbreaking test for bloodstream infections (BSI) and antimicrobial resistance (AMR), which uses whole blood specimens to detect and identify infections that lead to sepsis.
By rapidly identifying what infection a patient has, as well as any associated AMR, our test will provide clinicians with actionable information to help them select the best antibiotics to treat the disease.
![5fd0f38d6fb9661baa01a445_Clinically](https://www.dnae.com/wp-content/uploads/2024/03/5fd0f38d6fb9661baa01a445_Clinically.webp)
DNAe’s BSI/AMR test takes approximately 3-4 hours to complete and with regulatory clearance can deliver actionable results to the clinician at the point-of-need.
![5fca36d5800716ab274a61c2_pasted image 1183x280](https://www.dnae.com/wp-content/uploads/2024/03/5fca36d5800716ab274a61c2_pasted-image-1183x280-1.webp)
Urgent need: Mortality increases 7.6+% for every hour after onset of hypotension. Kumar et al. (2006) Critical Care Med.
Focused and fast
This one breakthrough test is enough to identify a broad range of possible bloodstream infectious organisms, as well as a selection of antimicrobial resistance genes.
Because microbial pathogens may be present at very low concentrations in the blood of infected patients (1 colony-forming unit per ml), the BSI/AMR test incorporates a sample preparation stage capable of extracting microbial DNA from a vacutainer of blood, which is subsequently amplified and identified.
![5fca36d58007168ded4a6187_sepsis copy-crop-u76241](https://www.dnae.com/wp-content/uploads/2024/03/5fca36d58007168ded4a6187_sepsis-copy-crop-u76241.webp)
By accurately diagnosing infections at an earlier stage, we can help to save the lives of patients.
![5fca36d580071682a74a6188_sepsis_detect_bug_chart_aw_2x-p-1600](https://www.dnae.com/wp-content/uploads/2024/03/5fca36d580071682a74a6188_sepsis_detect_bug_chart_aw_2x-p-1600.webp)